Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SIK1 | P57059 | 2/20 | 0.47 |
| ▸ | SIK2 | Q9H0K1 | 2/20 | 0.47 |
| ▸ | SIK3 | Q9Y2K2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081309 | 0.88 | OXTR (0.55) | OXTRMAPTSIK1SIK2SIK3 | |
| SCHEMBL8088529 | 0.80 | PRKDC (0.57) | OXTRMAPTALDH1A1SIK1SIK2 | |
| SCHEMBL23683820 | 0.78 | MAPT (0.54) | MAPTALDH1A1MRGPRX4MEN1PKM | |
| SCHEMBL7040523 | 0.76 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL7334838 | 0.75 | NOTUM (0.41) | PTK2MAPK10MAPK9MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7334841 | 0.74 | CYP1A2 (0.47) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2650247 | 0.73 | MAPT (0.78) | MAPTALDH1A1LMNAMRGPRX4 | |
| SCHEMBL8092952 | 0.72 | CYP1A2 (0.48) | MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8088577 | 0.72 | L3MBTL1 (0.44) | OXTRMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL8088563 | 0.72 | CYP1A2 (0.46) | MAPTALDH1A1LMNAMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |