Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9185703 | 0.97 | L3MBTL1 (0.41) | L3MBTL1MAPTLMNAATMKCNQ3 | |
| SCHEMBL5720159 | 0.86 | MAPT (0.43) | L3MBTL1MAPTLMNAATMKCNQ3 | |
| Diphenylmethanol SCHEMBL8081652 | 0.85 | KDM4E (0.43) | L3MBTL1MAPTLMNAATMKCNQ3 | |
| Diphenylmethanol SCHEMBL9185711 | 0.85 | KDM4E (0.43) | L3MBTL1MAPTLMNAATMKCNQ3 | |
| SCHEMBL8077096 | 0.84 | CFTR (0.57) | L3MBTL1MAPTLMNAATMCFTR | |
| SCHEMBL8077059 | 0.83 | ALDH1A1 (0.51) | L3MBTL1MAPTLMNAATMCFTR | |
| SCHEMBL9119780 | 0.82 | L3MBTL1 (0.43) | L3MBTL1MAPTLMNAATMNPSR1 | |
| SCHEMBL8076935 | 0.81 | CCR2 (0.50) | L3MBTL1KCNQ3KCNQ2KDM4E | |
| SCHEMBL8076970 | 0.80 | L3MBTL1 (0.52) | L3MBTL1MAPTLMNAATMCFTR | |
| SCHEMBL9188384 | 0.74 | CFTR (0.56) | L3MBTL1MAPTLMNAATMCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799198-B1 | ANTI-INFLAMMATORY COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2000-08-30 | — | — | EP | disclosed |
| US-5545669-A | Anti-inflammatory compounds | SMITHKLINE BEECHAM CORPORATION | 1996-08-13 | — | — | US | disclosed |
| WO-1995033460-A1 | ANTI-INFLAMMATORY COUMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-12-14 | — | — | WO | disclosed |
| US-5447957-A | Anti-inflammatory compounds | SMITHKLINE BEECHAM CORP. (US) | 1995-09-05 | — | — | US | disclosed |