Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL419 | 0.84 | SLC6A4 (0.46) | GP6AGTR2AGTR1 | |
| SCHEMBL417 | 0.84 | SLC6A4 (0.46) | GP6AGTR2AGTR1 | |
| SCHEMBL138 | 0.81 | AGTR1 (0.52) | AGTR2AGTR1 | |
| SCHEMBL136 | 0.81 | AGTR1 (0.52) | AGTR2AGTR1 | |
| SCHEMBL10587702 | 0.74 | AGTR1 (0.45) | AGTR2AGTR1 | |
| SCHEMBL10587697 | 0.74 | AGTR1 (0.45) | AGTR2AGTR1 | |
| SCHEMBL410 | 0.73 | AGTR2 (0.52) | AGTR2AGTR1 | |
| SCHEMBL408 | 0.73 | AGTR2 (0.52) | AGTR2AGTR1 | |
| SCHEMBL8080984 | 0.72 | AGTR1 (0.39) | AGTR2AGTR1 | |
| SCHEMBL11 | 0.71 | GP6 (0.49) | GP6AGTR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000508347-A | — | — | 2000-07-04 | — | — | JP | claimed |
| EP-0966282-A1 | USE OF ANGIOTENSIN II ANTAGONISTS TO TREAT SYMPTOMATIC HEART FAILURE | Merck & Co., Inc. (US) | 1999-12-29 | — | — | EP | claimed |
| WO-1998030216-A1 | USE OF ANGIOTENSIN II ANTAGONISTS TO TREAT SYMPTOMATIC HEART FAILURE | MERCK & CO., INC. (US) | 1998-07-16 | — | — | WO | claimed |