Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.41 |
| ▸ | NOS1 | P29475 | 3/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17053409 | 0.80 | MET (0.50) | METIDO1AXLTRPV1NOS1 | |
| SCHEMBL3671316 | 0.77 | TRPV1 (0.47) | METIDO1AXLTRPV1NOS1 | |
| SCHEMBL22808947 | 0.76 | MET (0.44) | METIDO1AXLTRPV1NOS1 | |
| SCHEMBL14102482 | 0.74 | NOS1 (0.49) | METIDO1AXLTRPV1NOS1 | |
| SCHEMBL8228261 | 0.74 | IDO1 (0.50) | METIDO1AXLTRPV1NOS1 | |
| Hydrochloric Acid SCHEMBL4683856 | 0.73 | NOS1 (0.47) | METIDO1AXLTRPV1NOS1 | |
| SCHEMBL22619200 | 0.72 | NOS1 (0.44) | METIDO1AXLTRPV1NOS1 | |
| SCHEMBL17739153 | 0.72 | CREBBP (0.56) | TRPV1 | |
| SCHEMBL17739088 | 0.72 | JAK1 (0.46) | METIDO1TRPV1 | |
| SCHEMBL4684070 | 0.71 | MET (0.45) | METIDO1AXLTRPV1NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147812-A2 | 4' SUBSTITUTED COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2008-12-04 | — | — | WO | disclosed |