Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2957205 | 0.85 | CTNNB1 (0.46) | FABP4KMT2ACTNNB1TP53DHODH | |
| Ammonia Solution, Strong SCHEMBL6532360 | 0.84 | CTNNB1 (0.46) | FABP4KMT2ACTNNB1CDK2TP53 | |
| SCHEMBL8072530 | 0.83 | GPR35 (0.46) | KMT2ANPC1RAB9AALDH1A1POLB | |
| SCHEMBL2952044 | 0.78 | PARP1 (0.46) | FABP4KMT2ANPC1RAB9ACTNNB1 | |
| SCHEMBL7656276 | 0.78 | P2RY14 (0.46) | GPR35 | |
| SCHEMBL8086618 | 0.76 | ALOX5 (0.52) | KMT2AMAOBFAAHALDH1A1CA12 | |
| SCHEMBL2954675 | 0.75 | FABP3 (0.40) | FABP4KMT2ACTNNB1TP53DHODH | |
| SCHEMBL2955515 | 0.75 | ALDH1A1 (0.47) | FABP4KMT2ANPC1RAB9ACTNNB1 | |
| SCHEMBL2960487 | 0.75 | NPC1 (0.41) | FABP4NPC1RAB9ACTNNB1TP53 | |
| SCHEMBL2954105 | 0.75 | ALDH1A1 (0.49) | FABP4KMT2ANPC1RAB9ACTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030967-A | AND/OR LIKE NEUROTROPHIC FACTOR (FOR EXAMPLE, NERVE GROWTH FACTOR (NGF), BRAIN-DERIVED NEUROTROPHIC FACTOR, NEUROTROPHIN-3, AND GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR)-LIKE ACTIVITY; OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-02-29 | — | — | US | disclosed |