Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4342270 | 0.83 | ALDH1A1 (0.58) | KDM4EHSD17B10EPHX1KMT2AMAPT | |
| SCHEMBL3782005 | 0.78 | KDM4E (0.68) | KDM4EHSD17B10EPHX1KMT2APOLB | |
| SCHEMBL2388970 | 0.77 | EPHX1 (0.70) | KDM4EHSD17B10EPHX1KMT2APOLB | |
| SCHEMBL7707267 | 0.76 | ALDH1A1 (0.61) | KDM4EHSD17B10KMT2ANPC1MAPT | |
| SCHEMBL3048096 | 0.75 | ALDH1A1 (0.55) | HSD17B10KMT2APOLBNPC1MAPT | |
| SCHEMBL6106176 | 0.75 | GAA (0.63) | KDM4EHSD17B10KMT2APOLBMAPT | |
| SCHEMBL1952367 | 0.75 | POLB (0.67) | KDM4EHSD17B10EPHX1KMT2APOLB | |
| SCHEMBL30296233 | 0.75 | KDM4E (0.59) | KDM4EHSD17B10EPHX1KMT2APOLB | |
| SCHEMBL1249700 | 0.75 | KCNMA1 (0.64) | KDM4EHSD17B10KMT2APOLBNPC1 | |
| SCHEMBL9403860 | 0.75 | KDM4E (0.59) | KDM4EHSD17B10EPHX1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0911317-B1 | Process for the preparation of 2-hydroyalkyl paraphenylenediamines, novel 2-hydroxyalkyl paraphenylenediamines, their use for oxydative dyeing, dye compositions and dyeing processes | OREAL (FR) | 2000-09-13 | — | — | EP | disclosed |