SCHEMBL8082401

SCHEMBL8082401

N[C@H]1CCCN(CC(=O)OCc2ccccc2)C1=O

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
CYP2C19 P33261 2/20 0.44
ALDH1A1 P00352 1/20 0.43
MAPK1 P28482 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
CASP3 P42574 1/20 0.43
FKBP1A P62942 2/20 0.42
ACE P12821 2/20 0.42
F2 P00734 1/20 0.41
MME P08473 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8082397 0.99 SMN1; SMN2 (0.43) SMN1; SMN2CYP2C19ALDH1A1MAPK1L3MBTL1
Hydrochloric Acid SCHEMBL8082404 0.99 SMN1; SMN2 (0.43) SMN1; SMN2CYP2C19ALDH1A1MAPK1L3MBTL1
SCHEMBL4985086 0.96 CASP3 (0.46) SMN1; SMN2CYP2C19ALDH1A1MAPK1L3MBTL1
SCHEMBL4985094 0.96 CASP3 (0.46) SMN1; SMN2CYP2C19ALDH1A1MAPK1L3MBTL1
Hydrochloric Acid SCHEMBL10795974 0.95 CASP3 (0.46) SMN1; SMN2CYP2C19ALDH1A1MAPK1L3MBTL1
Hydrochloric Acid SCHEMBL10795978 0.95 CASP3 (0.46) SMN1; SMN2CYP2C19ALDH1A1MAPK1L3MBTL1
SCHEMBL10915168 0.95 CASP3 (0.46) SMN1; SMN2CYP2C19CASP3FKBP1AACE
SCHEMBL10896117 0.95 CASP3 (0.46) SMN1; SMN2CYP2C19CASP3FKBP1AACE
SCHEMBL17949283 0.92 SMN1; SMN2 (0.46) SMN1; SMN2CYP2C19ALDH1A1MAPK1L3MBTL1
SCHEMBL15368459 0.85 PER2 (0.45) SMN1; SMN2ALDH1A1MAPK1L3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250197869-A1 Ribosome-Mediated Incorporation of Peptides and Peptidomimetics ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2025-06-19 US disclosed
US-12264318-B2 Ribosome-mediated incorporation of peptides and peptidomimetics ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2025-04-01 US disclosed
US-20230046194-A1 Ribosome-Mediated Incorporation of Peptides and Peptidomimetics ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2023-02-16 US disclosed
US-11434492-B2 Ribosome-mediated incorporation of peptides and peptidomimetics ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2022-09-06 US disclosed
US-20180002709-A1 RIBOSOME-MEDIATED INCORPORATION OF PEPTIDES AND PEPTIDOMIMETICS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-01-04 US disclosed
WO-2016118877-A1 RIBOSOME-MEDIATED INCORPORATION OF PEPTIDES AND PEPTIDOMIMETICS ARIZON BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2016-07-28 WO disclosed
US-6034215-A 3-amino-2-oxo-1-piperidnercetic derivatives as enzyme inhibitors CORVAS INTERNATIONAL, INC. (US) 2000-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180002709-A1 RIBOSOME-MEDIATED INCORPORATION OF PEPTIDES AND PEPTIDOMIMETICS NPEPPS, DNPEP, AARS1 SMN1; SMN2 2495/4885CYP2C19 4615/4885ALDH1A1 4835/4885
US-20230046194-A1 Ribosome-Mediated Incorporation of Peptides and Peptidomimetics NPEPPS, DNPEP, AARS1 SMN1; SMN2 2495/4885CYP2C19 4615/4885ALDH1A1 4835/4885
US-12264318-B2 Ribosome-mediated incorporation of peptides and peptidomimetics NPEPPS, DNPEP, AARS1 SMN1; SMN2 2495/4885CYP2C19 4615/4885ALDH1A1 4835/4885
US-20250197869-A1 Ribosome-Mediated Incorporation of Peptides and Peptidomimetics NPEPPS, DNPEP, AARS1 SMN1; SMN2 2495/4885CYP2C19 4615/4885ALDH1A1 4835/4885
US-11434492-B2 Ribosome-mediated incorporation of peptides and peptidomimetics NPEPPS, DNPEP, AARS1 SMN1; SMN2 2495/4885CYP2C19 4615/4885ALDH1A1 4835/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.