Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287127 | 0.87 | HDAC8 (0.33) | HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL10287133 | 0.86 | CNR2 (0.31) | — | |
| SCHEMBL808249 | 0.85 | HDAC4 (0.30) | HDAC1 | |
| SCHEMBL10287198 | 0.84 | HDAC6 (0.34) | HDAC6HDAC1HDAC8SCN9AHDAC5 | |
| SCHEMBL10287123 | 0.76 | POLB (0.41) | HDAC6HDAC1HDAC8SCN9A | |
| SCHEMBL808041 | 0.74 | TRPV1 (0.39) | — | |
| SCHEMBL808240 | 0.72 | HDAC6 (0.35) | HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL10287296 | 0.72 | ATR (0.42) | — | |
| SCHEMBL10287533 | 0.71 | ADRA2A (0.33) | — | |
| SCHEMBL795333 | 0.70 | PIK3CA (0.41) | HDAC6HDAC1HDAC8SCN9AHDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |