Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 7/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808247 | 0.89 | STAT3 (0.30) | — | |
| SCHEMBL808333 | 0.81 | NPC1 (0.37) | HDAC6HDAC4HDAC8ALDH1A1HDAC1 | |
| SCHEMBL10287196 | 0.81 | HDAC4 (0.37) | HDAC6HDAC4HDAC8S1PR1ALDH1A1 | |
| SCHEMBL808161 | 0.81 | HDAC4 (0.32) | HDAC6HDAC4HDAC8 | |
| SCHEMBL808235 | 0.80 | HDAC6 (0.34) | HDAC6HDAC4HDAC8HDAC1 | |
| SCHEMBL807993 | 0.78 | GRM5 (0.39) | HDAC6HDAC4HDAC8S1PR1PPARG | |
| SCHEMBL10287153 | 0.77 | HDAC6 (0.33) | HDAC6HDAC8HDAC1HDAC5 | |
| SCHEMBL807785 | 0.76 | HDAC4 (0.30) | HDAC6HDAC4HDAC8 | |
| SCHEMBL10286912 | 0.76 | GABRA1 (0.36) | HDAC6HDAC4HDAC8HDAC1 | |
| SCHEMBL808042 | 0.76 | LIPE (0.35) | HDAC6HDAC4HDAC8S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |