Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | HAVCR2 | Q8TDQ0 | 5/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287533 | 0.76 | ADRA2A (0.33) | ALDH1A1 | |
| SCHEMBL10287136 | 0.73 | ALDH1A1 (0.41) | S1PR1KDM4ESMN1; SMN2TP53MAPT | |
| SCHEMBL808244 | 0.72 | HDAC6 (0.34) | — | |
| SCHEMBL10287123 | 0.69 | POLB (0.41) | HAVCR2TP53MAPTMEN1KMT2A | |
| SCHEMBL808249 | 0.69 | HDAC4 (0.30) | — | |
| SCHEMBL15477231 | 0.66 | S1PR1 (0.50) | ATRS1PR1USP30ALOX5APKDM4E | |
| SCHEMBL10287187 | 0.66 | ALDH1A1 (0.45) | S1PR1KDM4ESMN1; SMN2TP53MAPT | |
| SCHEMBL24921187 | 0.64 | S1PR1 (0.64) | S1PR1USP30ALOX5APKDM4ESMN1; SMN2 | |
| SCHEMBL807993 | 0.64 | GRM5 (0.39) | S1PR1SMN1; SMN2TP53MAPTPPARG | |
| SCHEMBL808315 | 0.64 | SMN1; SMN2 (0.39) | SMN1; SMN2MEN1TSHRKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035023-A1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2012-03-22 | — | — | WO | disclosed |