Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2219779 | 0.81 | GNAI3 (0.47) | MEN1LMNAKMT2APTGS1PTGS2 | |
| SCHEMBL24312050 | 0.77 | CA1 (0.35) | MEN1ALDH1A1LMNAKMT2ACA1 | |
| SCHEMBL29018282 | 0.74 | TP53 (0.44) | CYP3A4HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL20752748 | 0.72 | SLC6A5 (0.48) | CYP3A4MMP2HDAC3HDAC1HDAC2 | |
| SCHEMBL2539135 | 0.70 | ALDH1A1 (0.42) | MEN1ALDH1A1LMNAKMT2ACA1 | |
| SCHEMBL22529820 | 0.68 | ALDH1A1 (0.43) | MEN1ALDH1A1KMT2A | |
| SCHEMBL20732371 | 0.67 | PTGS1 (0.44) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL31087111 | 0.67 | PAOX (0.44) | MEN1KMT2APAOX | |
| SCHEMBL27527215 | 0.67 | GNAI3 (0.48) | MEN1LMNAKMT2ACA1CA2 | |
| SCHEMBL4837664 | 0.67 | HDAC6 (0.72) | CYP3A4HDAC3HDAC1HDAC2HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041999-A1 | THROMBOGENIC POLYPEPTIDE CHIMERAS AND CONJUGATES HAVING ACTIVITY DEPENDENT UPON ASSOCIATION WITH TUMOR VASCULAR ENDOTHELIUM | Nuvas LLC (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999032143-A1 | THROMBOGENIC POLYPEPTIDE CHIMERAS AND CONJUGATES HAVING ACTIVITY DEPENDENT UPON ASSOCIATION WITH TUMOR VASCULAR ENDOTHELIUM | NUVAS LLC (US) | 1999-07-01 | — | — | WO | disclosed |