Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 1/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29018282 | 0.87 | TP53 (0.44) | CA1CA2RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL14524207 | 0.83 | GAA (0.39) | GNAI3GNAO1GNAI1EPHX2LMNA | |
| SCHEMBL28901865 | 0.83 | KMT2A (0.45) | HSP90AA1EPHX2FAAHMEN1KMT2A | |
| SCHEMBL8082777 | 0.81 | CYP3A4 (0.41) | CA1CA2LMNAMEN1KMT2A | |
| SCHEMBL2539135 | 0.79 | ALDH1A1 (0.42) | CA1CA2LMNAMEN1KMT2A | |
| SCHEMBL27527215 | 0.78 | GNAI3 (0.48) | GNAI3GNAO1GNAI1HSP90AA1CA1 | |
| SCHEMBL29280200 | 0.75 | DGKA (0.41) | LMNAFAAHKMT2APTGS1PTGS2 | |
| SCHEMBL14877935 | 0.72 | PTGS1 (0.57) | FAAHMEN1KMT2APTGS1PTGS2 | |
| SCHEMBL9190539 | 0.72 | GNAI3 (0.46) | GNAI3GNAO1GNAI1HSP90AA1CA1 | |
| SCHEMBL9190544 | 0.72 | GNAI3 (0.46) | GNAI3GNAO1GNAI1HSP90AA1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260000777-A1 | NECTIN-4 ANTIBODY CONJUGATES AND USES THEREOF | ARARIS BIOTECH AG (CH) | 2026-01-01 | — | — | US | disclosed |
| US-10266620-B2 | Coating agents and coated articles | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2019-04-23 | — | — | US | disclosed |
| US-20170081435-A1 | COATING AGENTS AND COATED ARTICLES | INNOVATIVE SURFACE TECH INC (US) | 2017-03-23 | — | — | US | disclosed |
| US-9539371-B2 | Coating agents and coated articles | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2017-01-10 | — | — | US | disclosed |
| US-9518118-B2 | Anti-HER2 antibodies and immunoconjugates | GENENTECH, INC. (US) | 2016-12-13 | — | — | US | disclosed |
| EP-2516567-B1 | COATING AGENTS AND COATED ARTICLES | INNOVATIVE SURFACE TECHNOLOGIES INC (US) | 2016-08-03 | — | — | EP | disclosed |
| US-20160096893-A1 | ANTI-HER2 ANTIBODIES AND IMMUNOCONJUGATES | GENENTECH, INC. (US) | 2016-04-07 | — | — | US | disclosed |
| US-20150359944-A1 | COATING AGENTS AND COATED ARTICLES | INNOVATIVE SURFACE TECHNOLOGIES INC (US) | 2015-12-17 | — | — | US | disclosed |
| US-20140017265-A1 | Terminally Modified Polymers and Conjugates Thereof | MERSANA THERAPEUTICS, INC. | 2014-01-16 | — | — | US | disclosed |
| EP-2516567-A1 | COATING AGENTS AND COATED ARTICLES | Innovative Surface Technologies, Inc. (US) | 2012-10-31 | — | — | EP | disclosed |
| US-20120258313-A1 | COATING AGENTS AND COATED ARTICLES | INNOVATIVE SURFACE TECHNOLOGIES, INC. | 2012-10-11 | — | — | US | disclosed |
| WO-2011084811-A1 | COATING AGENTS AND COATED ARTICLES | INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) | 2011-07-14 | — | — | WO | disclosed |
| US-20040242854-A1 | Chemical capture reagent | GE HEALTHCARE UK LIMITED (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-1402268-A2 | CHEMICAL CAPTURE REAGENT | Amersham Biosciences UK Limited (GB) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003005026-A2 | CHEMICAL CAPTURE REAGENT | AMERSHAM BIOSCIENCES UK LIMITED (GB) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260000777-A1 | NECTIN-4 ANTIBODY CONJUGATES AND USES THEREOF | NECTIN4, IGSF11, VSIG8 | GNAI3 3295/4885GNAO1 3826/4885GNAI1 3706/4885 |
| US-20140017265-A1 | Terminally Modified Polymers and Conjugates Thereof | MALT1, ALG1, PRMT3 | GNAI3 3870/4885GNAO1 3900/4885GNAI1 4305/4885 |
| US-20160096893-A1 | ANTI-HER2 ANTIBODIES AND IMMUNOCONJUGATES | ERBB2, EGFR, ERBB3 | GNAI3 1413/4885GNAO1 4285/4885GNAI1 2229/4885 |
| US-20040242854-A1 | Chemical capture reagent | SPPL2B, PRXL2A, PLG | GNAI3 3241/4885GNAO1 3648/4885GNAI1 2216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.