Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091231 | 0.93 | KDM4E (0.40) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8083224 | 0.91 | ALDH1A1 (0.59) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9047303 | 0.90 | ALDH1A1 (0.39) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8089691 | 0.83 | TOP2A (0.49) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9047385 | 0.83 | KDM4E (0.32) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8091409 | 0.82 | KDM4E (0.40) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9044116 | 0.81 | ALDH1A1 (0.47) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8092759 | 0.80 | ALDH1A1 (0.54) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9053933 | 0.79 | ALDH1A1 (0.59) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9053930 | 0.79 | ALDH1A1 (0.59) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018054-A | INTERMEDIATE COMPOUNDS FOR PREPARING NOVEL QUINOLONE AND NAPHTHYRIDONE DERIVATIVES WHICH ARE SUBSTITUTED IN THE 7-POSITION BY A PARTIALLY HYDROGENATED ISOINDOLINYL RING, USE AS ANTIBACTERIAL AGENTS AND AS FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-25 | — | — | US | disclosed |
| US-5556979-A | ANIMAL FEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-17 | — | — | US | disclosed |