Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9047385 | 0.93 | KDM4E (0.32) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL9044116 | 0.91 | ALDH1A1 (0.47) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL8083017 | 0.90 | ALDH1A1 (0.49) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL9044987 | 0.84 | KDM4E (0.39) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL9043731 | 0.83 | KDM4E (0.33) | ALDH1A1KDM4EHPGD | |
| SCHEMBL8091231 | 0.83 | KDM4E (0.40) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL8203931 | 0.81 | LMNA (0.35) | ALDH1A1POLBOPRM1TOP1KDM4E | |
| SCHEMBL9046791 | 0.81 | ALDH1A1 (0.43) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| SCHEMBL8083224 | 0.81 | ALDH1A1 (0.59) | ALDH1A1POLBCHRM2CHRM1OPRM1 | |
| Hydrochloric Acid SCHEMBL9045026 | 0.80 | KCNH2 (0.35) | ALDH1A1POLBCHRM2CHRM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588166-B1 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1996-06-05 | — | — | EP | disclosed |
| EP-0588166-A2 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-03-23 | — | — | EP | disclosed |