SCHEMBL8083103

SCHEMBL8083103

N#CCC[Si](Cl)(Cl)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 2/20 0.33
CYP1A2 P05177 1/20 0.33
GLA P06280 1/20 0.33
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HTT P42858 2/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GAA P10253 1/20 0.31
MCL1 Q07820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1345729 0.88 ATM (0.37) LMNAMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL8087267 0.83 LMNA (0.34) LMNAMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL4951387 0.81 ATM (0.33) LMNAALDH1A1TSHRGLAATM
SCHEMBL8075522 0.80 LMNA (0.33) LMNAMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL706034 0.79 TSHR (0.33) ALDH1A1TSHRHSD17B10
SCHEMBL703162 0.75 MAPT (0.31) TSHRMAPT
SCHEMBL705203 0.75 MAPT (0.31) TSHRMAPT
SCHEMBL11691875 0.73 ALDH1A1 (0.32) LMNAKMT2AALDH1A1
SCHEMBL3225896 0.73
SCHEMBL10786027 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109319750-B Method for preparing alpha-silicon nitride nanobelt by microwave heating 江西宏柏新材料股份有限公司 2020-10-09 CN claimed
CN-109319750-A A kind of method that microwave heating prepares α-siliconnitride nanobelt 江西宏柏新材料股份有限公司 2019-02-12 CN claimed
CN-109319750-B Method for preparing alpha-silicon nitride nanobelt by microwave heating 江西宏柏新材料股份有限公司 2020-10-09 CN disclosed
EP-0633265-B1 Process for preparation of beta-cyanoalkylsilanes DOW CORNING (US) 2000-10-25 EP disclosed
EP-0525997-B1 Catalysts for addition of silicon hydrides to alpha, beta-unsaturated olefinic nitriles DOW CORNING (US) 1996-08-21 EP disclosed
EP-0633265-A1 Process for preparation of beta-cyanoalkylsilanes DOW CORNING CORPORATION (US) 1995-01-11 EP disclosed
US-5374756-A Addition of trihalosilane to alpha-beta unsaturated olefinic nitriles DOW CORNING CORPORATION (US) 1994-12-20 US disclosed
EP-0618210-A1 Process for preparation of beta-cyanoalkylsilanes using ruthenium catalyst DOW CORNING CORPORATION (US) 1994-10-05 EP disclosed
US-5332848-A From unsaturated nitrile and trihalosilane DOW CORNING CORPORATION (US) 1994-07-26 US disclosed
US-5326894-A β-cyanoalkylsilane preparation using divinylbenzene/4-vinylpyridine copolymer resin as catalyst DOW CORNING CORPORATION (US) 1994-07-05 US disclosed
US-5312945-A Process for preparation of β-cyanoalkylsilanes using ruthenium catalyst DOW CORNING CORPORATION (US) 1994-05-17 US disclosed
US-5283348-A Process for preparation of β-cyanoalkylsilanes DOW CORNING CORPORATION (US) 1994-02-01 US disclosed
EP-0525997-A1 Catalysts for addition of silicon hydrides to alpha, beta-unsaturated olefinic nitriles DOW CORNING CORPORATION (US) 1993-02-03 EP disclosed
EP-0520645-A1 Process for preparation of beta-cyanoalkylsilanes DOW CORNING CORPORATION (US) 1992-12-30 EP disclosed
US-5126469-A Supported catalysts for addition of silicon hydrides to α,β-unsaturated olefinic nitriles DOW CORNING CORPORATION (US) 1992-06-30 US disclosed
US-5126468-A Diamine and copper or copper compound DOW CORNING CORPORATION (US) 1992-06-30 US disclosed
US-5103033-A Catalytic reaction of unsaturated nitriles and silicon hydride DOW CORNING CORPORATION (US) 1992-04-07 US disclosed