Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083103 | 0.83 | LMNA (0.34) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL8075522 | 0.80 | LMNA (0.33) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL703091 | 0.79 | TSHR (0.33) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL1345729 | 0.76 | ATM (0.37) | LMNAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL703425 | 0.75 | ESR1 (0.34) | TSHR | |
| SCHEMBL713816 | 0.75 | ESR1 (0.34) | TSHR | |
| SCHEMBL705990 | 0.71 | TP53 (0.35) | GAAKMT2AALDH1A1TSHRTP53 | |
| SCHEMBL6669212 | 0.71 | ALDH1A1 (0.32) | LMNAGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL4951387 | 0.70 | ATM (0.33) | LMNAALDH1A1TSHRGLAATM | |
| SCHEMBL8908265 | 0.70 | SLC9A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0633265-B1 | Process for preparation of beta-cyanoalkylsilanes | DOW CORNING (US) | 2000-10-25 | — | — | EP | disclosed |
| EP-0525997-B1 | Catalysts for addition of silicon hydrides to alpha, beta-unsaturated olefinic nitriles | DOW CORNING (US) | 1996-08-21 | — | — | EP | disclosed |
| US-5283348-A | Process for preparation of β-cyanoalkylsilanes | DOW CORNING CORPORATION (US) | 1994-02-01 | — | — | US | disclosed |
| EP-0525997-A1 | Catalysts for addition of silicon hydrides to alpha, beta-unsaturated olefinic nitriles | DOW CORNING CORPORATION (US) | 1993-02-03 | — | — | EP | disclosed |
| EP-0520645-A1 | Process for preparation of beta-cyanoalkylsilanes | DOW CORNING CORPORATION (US) | 1992-12-30 | — | — | EP | disclosed |
| US-5126469-A | Supported catalysts for addition of silicon hydrides to α,β-unsaturated olefinic nitriles | DOW CORNING CORPORATION (US) | 1992-06-30 | — | — | US | disclosed |
| US-5126468-A | Diamine and copper or copper compound | DOW CORNING CORPORATION (US) | 1992-06-30 | — | — | US | disclosed |
| US-5103033-A | Catalytic reaction of unsaturated nitriles and silicon hydride | DOW CORNING CORPORATION (US) | 1992-04-07 | — | — | US | disclosed |