Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081953 | 0.80 | PPARA (0.42) | PPARAPPARGHTR1AADRA2AADRA2B | |
| SCHEMBL8082709 | 0.80 | PPARG (0.56) | PPARAPPARGHTR1AADRA2AADRA2B | |
| SCHEMBL8074435 | 0.79 | PPARA (0.41) | PPARAPPARGHTR1AADRA2AADRA2B | |
| SCHEMBL8086173 | 0.79 | PPARA (0.41) | PPARAPPARGHTR1AADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL8074440 | 0.79 | PPARG (0.55) | PPARAPPARGHTR1AADRA2AADRA2B | |
| SCHEMBL8074376 | 0.78 | POLB (0.43) | PPARAPPARGHTR1AADRA2AADRA2B | |
| SCHEMBL1245341 | 0.71 | PPARA (0.49) | PPARAPPARGKMT2ASMN1; SMN2LMNA | |
| SCHEMBL8527208 | 0.71 | HTR1A (0.42) | PPARAPPARGHTR1AADRA2AADRA2B | |
| SCHEMBL8935797 | 0.71 | PPARA (0.49) | PPARAPPARGKMT2ASMN1; SMN2LMNA | |
| SCHEMBL26127073 | 0.71 | RECQL (0.40) | PPARAMEN1KMT2ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063810-A | ENANTIOMORPHS | SYNTHELABO (FR) | 2000-05-16 | — | — | US | disclosed |