Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046354 | 0.91 | KDM4E (0.44) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL8092868 | 0.89 | KDM4E (0.55) | HSD17B10KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL8092840 | 0.89 | HSD17B10 (0.41) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL8084270 | 0.87 | HSD17B10 (0.53) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL8095031 | 0.84 | DRD3 (0.59) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9045440 | 0.82 | ALDH1A1 (0.35) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL9045493 | 0.82 | KDM4E (0.44) | HSD17B10KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL9095828 | 0.79 | KCNH2 (0.48) | HSD17B10KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL8091409 | 0.78 | KDM4E (0.40) | HSD17B10KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL9044779 | 0.78 | KDM4E (0.43) | HSD17B10KDM4EALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018054-A | INTERMEDIATE COMPOUNDS FOR PREPARING NOVEL QUINOLONE AND NAPHTHYRIDONE DERIVATIVES WHICH ARE SUBSTITUTED IN THE 7-POSITION BY A PARTIALLY HYDROGENATED ISOINDOLINYL RING, USE AS ANTIBACTERIAL AGENTS AND AS FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-25 | — | — | US | disclosed |