Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8092840 | 0.91 | HSD17B10 (0.41) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL9046354 | 0.90 | KDM4E (0.44) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL9045493 | 0.88 | KDM4E (0.44) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL9047814 | 0.84 | ALDH1A1 (0.35) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL8083248 | 0.82 | DRD3 (0.53) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL8092868 | 0.81 | KDM4E (0.55) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL9044779 | 0.80 | KDM4E (0.43) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL9048740 | 0.79 | ADRB2 (0.40) | ALDH1A1KDM4EHSD17B10HPGDLMNA | |
| SCHEMBL9049171 | 0.78 | KCNH2 (0.34) | — | |
| SCHEMBL9043731 | 0.78 | KDM4E (0.33) | ALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588166-B1 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1996-06-05 | — | — | EP | disclosed |
| EP-0588166-A2 | Antibacterial 7-isoindolinyl-quinolone and naphthyridone derivatives | BAYER AG (DE) | 1994-03-23 | — | — | EP | disclosed |