Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1295475 | 0.78 | ALOX5 (0.47) | KDM4EALDH1A1SMN1; SMN2ALOX5RIPK1 | |
| SCHEMBL22607861 | 0.78 | TRPM8 (0.43) | KDM4ESMN1; SMN2NLRP3PKMTRPM8 | |
| SCHEMBL7960171 | 0.78 | NPSR1 (0.46) | ALDH1A1SMN1; SMN2PKMTRPM8LMNA | |
| SCHEMBL6627880 | 0.77 | ALDH1A1 (0.43) | KDM4EALDH1A1SMN1; SMN2ALOX5PKM | |
| SCHEMBL6661039 | 0.77 | ALOX5 (0.50) | KDM4EALDH1A1SMN1; SMN2ALOX5PKM | |
| SCHEMBL25078271 | 0.76 | TSHR (0.49) | KDM4EALDH1A1PKMTRPM8CYP1A2 | |
| SCHEMBL2779791 | 0.76 | TRPM8 (0.45) | SMN1; SMN2PKMTRPM8LMNAGAA | |
| SCHEMBL20543517 | 0.73 | RIPK1 (0.42) | KDM4EALDH1A1SMN1; SMN2ALOX5PKM | |
| SCHEMBL20543515 | 0.73 | RIPK1 (0.42) | KDM4EALDH1A1SMN1; SMN2ALOX5PKM | |
| SCHEMBL31549227 | 0.73 | MAPK1 (0.45) | KDM4EALDH1A1SMN1; SMN2PKMTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100220-A | PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT | 2000-08-08 | — | — | US | disclosed |
| US-6025383-A | Substituted thiophene derivatives as pesticides and herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-15 | — | — | US | disclosed |