Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
| ▸ | NPY4R | P50391 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091675 | 0.89 | MAPT (0.34) | MAPTLMNATP53MEN1KMT2A | |
| SCHEMBL8090174 | 0.88 | F2 (0.39) | MEN1KMT2AF2SPHK1 | |
| SCHEMBL8095211 | 0.86 | MMP8 (0.42) | KMT2ASPHK1 | |
| SCHEMBL8095279 | 0.84 | NPY4R (0.38) | NPY1RNPY4R | |
| SCHEMBL8095146 | 0.83 | F2 (0.37) | MAPTHPGDF2SPHK1 | |
| SCHEMBL8098206 | 0.82 | C3AR1 (0.35) | SMN1; SMN2NPY1RNPY4R | |
| SCHEMBL8091524 | 0.82 | F2 (0.37) | MAPTHPGDALDH1A1F2SPHK1 | |
| SCHEMBL8091579 | 0.82 | MTNR1A (0.41) | ALDH1A1POLBPARP1 | |
| SCHEMBL8090189 | 0.81 | MMP8 (0.37) | MEN1KMT2AF2SPHK1 | |
| SCHEMBL8098060 | 0.81 | EPHX1 (0.36) | LMNAMEN1KMT2ASMN1; SMN2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |