Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | FABP1 | P07148 | 2/20 | 0.55 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9997278 | 0.91 | PFKFB3 (0.67) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL15689680 | 0.85 | ALDH1A1 (0.61) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL19561959 | 0.85 | MEN1 (0.67) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL17200980 | 0.82 | MEN1 (0.69) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL2702246 | 0.82 | ALDH1A1 (0.76) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL30708093 | 0.82 | ALDH1A1 (0.76) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL808364 | 0.80 | ALDH1A1 (1.00) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL5072751 | 0.78 | MEN1 (0.71) | ALDH1A1GAAMEN1KMT2AMMP2 | |
| SCHEMBL13602199 | 0.77 | MEN1 (0.72) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL9616679 | 0.76 | GAA (0.62) | ALDH1A1HTTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3056198-A2 | USE OF COMPOUNDS FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS TO CHONDROCYTES | MSP Co., Ltd (KR) | 2016-08-17 | — | — | EP | claimed |
| EP-2617415-B1 | USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS | CATHOLIC KWANDONG UNIVERSITY INDUSTRY FOUNDATION (KR) | 2016-04-20 | — | — | EP | claimed |
| US-20150252003-A1 | Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells | MSP CO., LTD. (KR) | 2015-09-10 | — | — | US | claimed |
| US-9068166-B2 | Use of compounds for inducing differentiation of mesenchymal stem cells to chondrocytes | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2015-06-30 | — | — | US | claimed |
| US-20130236969-A1 | Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2013-09-12 | — | — | US | claimed |
| EP-2617415-A2 | USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS | Industry-Academic Cooperation Foundation, Yonsei University (KR) | 2013-07-24 | — | — | EP | claimed |
| US-9757375-B2 | Compounds that inhibit human DNA ligases and methods of treating cancer | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2017-09-12 | — | — | US | disclosed |
| EP-3056198-A2 | USE OF COMPOUNDS FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS TO CHONDROCYTES | MSP Co., Ltd (KR) | 2016-08-17 | — | — | EP | disclosed |
| EP-2617415-B1 | USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS | CATHOLIC KWANDONG UNIVERSITY INDUSTRY FOUNDATION (KR) | 2016-04-20 | — | — | EP | disclosed |
| US-20150252003-A1 | Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells | MSP CO., LTD. (KR) | 2015-09-10 | — | — | US | disclosed |
| US-20150252003-A1 | Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells | MSP CO., LTD. (KR) | 2015-09-10 | — | — | US | disclosed |
| US-20150252003-A1 | Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells | MSP CO., LTD. (KR) | 2015-09-10 | — | — | US | disclosed |
| US-9068166-B2 | Use of compounds for inducing differentiation of mesenchymal stem cells to chondrocytes | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2015-06-30 | — | — | US | disclosed |
| US-9068166-B2 | Use of compounds for inducing differentiation of mesenchymal stem cells to chondrocytes | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2015-06-30 | — | — | US | disclosed |
| US-9068166-B2 | Use of compounds for inducing differentiation of mesenchymal stem cells to chondrocytes | INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY (KR) | 2015-06-30 | — | — | US | disclosed |
| US-20130236969-A1 | Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes | INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY (KR) | 2013-09-12 | — | — | US | disclosed |
| EP-2617415-A2 | USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS | Industry-Academic Cooperation Foundation, Yonsei University (KR) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012036512-A2 | USE OF A COMPOUND FOR INDUCING DIFFERENTIATION OF MESENCHYMAL STEM CELLS INTO CARTILAGE CELLS | 연세대학교 산학협력단 (KR) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130236969-A1 | Use of Compounds for Inducing Differentiation of Mesenchymal Stem Cells to Chondrocytes | COL2A1, MYADM, COL1A1 | ALDH1A1 47/4885HTT 4053/4885GAA 2400/4885 |
| US-20150252003-A1 | Use of a Compound for Inducing Differentiation of Mesenchymal Stem Cells into Cartilage Cells | COL2A1, MYADM, COL1A1 | ALDH1A1 23/4885HTT 4166/4885GAA 2243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.