Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | MMP12 | P39900 | 2/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | AGXT | P21549 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 2/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | CFD | P00746 | 2/20 | 0.49 |
| ▸ | F11 | P03951 | 2/20 | 0.49 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26240902 | 0.86 | ALDH1A1 (0.47) | POLBMRGPRX4ALDH1A1 | |
| SCHEMBL8085256 | 0.85 | RAB9A (0.53) | AGXTFFAR1ALDH1A1 | |
| SCHEMBL112859 | 0.84 | ALDH1A1 (0.64) | ALDH1A1 | |
| SCHEMBL487699 | 0.83 | ALDH1A1 (0.70) | MMP1MMP2MMP12MMP9AGXT | |
| Hydrochloric Acid SCHEMBL29090140 | 0.83 | ALDH1A1 (0.62) | ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27788705 | 0.83 | ALDH1A1 (0.62) | ALDH1A1 | |
| SCHEMBL7208472 | 0.81 | ENPP2 (0.46) | ALDH1A1ENPP2 | |
| SCHEMBL22066497 | 0.81 | MMP1 (0.56) | MMP1MMP2MMP12MMP9FFAR1 | |
| Acetic Acid SCHEMBL27664299 | 0.81 | ALDH1A1 (0.66) | ALDH1A1 | |
| SCHEMBL8402521 | 0.81 | MMP1 (0.55) | MMP1MMP2MMP12MMP9AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080286233-A1 | PIPERIZINYL MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080286233-A1 | PIPERIZINYL MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | PRSS1, HPN, PREP | MMP1 501/4885MMP2 117/4885MMP12 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.