SCHEMBL8083875

SCHEMBL8083875

CCCCO[Si](C)(OC)OCCCC

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
TSHR P16473 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP19A1 P11511 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
LMNA P02545 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL838422 0.95 ADRB2 (0.38) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL1608650 0.93 ADRB2 (0.33) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL1608021 0.92 DNM1 (0.35) TSHRALDH1A1CA1CA2LMNA
SCHEMBL6295813 0.87 DNM1 (0.35) TSHRALDH1A1CA1CA2LMNA
SCHEMBL93421 0.86 ADRB2 (0.43) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL25277699 0.85 DNM1 (0.39) TSHRALDH1A1CA1CA2
SCHEMBL2035776 0.85 ADRB2 (0.35) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL31506910 0.85 DNM1 (0.39) TSHRALDH1A1CA1CA2
SCHEMBL31233501 0.85 DNM1 (0.39) TSHRALDH1A1CA1CA2
SCHEMBL28404018 0.85 DNM1 (0.39) TSHRALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0691362-B1 Method of producing organopolysiloxanes containing hydrolyzable functional groups, and curable resin composition using said organopolysiloxanes SHINETSU CHEMICAL CO (JP) 2000-10-25 EP disclosed
US-5633311-A ROOM TEMPERATURE CURABLE RESIN SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-05-27 US disclosed
EP-0691362-A2 Method of producing organopolysiloxanes containing hydrolyzable functional groups, and curable resin composition using said organopolysiloxanes Shin-Etsu Chemical Co., Ltd. (JP) 1996-01-10 EP disclosed
US-4125507-A Process for priming and compositions therefor DOW CORNING CORPORATION (US) 1978-11-14 US disclosed
US-3975554-A Process for priming DOW CORNING CORPORATION (US) 1976-08-17 US disclosed