Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | CASP3 | P42574 | 2/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084754 | 0.91 | CYP1A2 (0.49) | CYP1A2RAB9ANPC1ALDH1A1POLB | |
| SCHEMBL8076758 | 0.89 | CYP1A2 (0.47) | CYP1A2RAB9ANPC1ALDH1A1POLB | |
| SCHEMBL8084118 | 0.88 | THRA (0.52) | CYP1A2RAB9ANPC1ALDH1A1POLB | |
| SCHEMBL8088063 | 0.83 | CYP1A2 (0.46) | CYP1A2RAB9ANPC1ALDH1A1POLB | |
| SCHEMBL8076747 | 0.80 | CYP1A2 (0.55) | CYP1A2RAB9ANPC1ALDH1A1POLB | |
| SCHEMBL8089833 | 0.80 | PPARG (0.57) | CYP1A2ALDH1A1POLBKDM4EKMT2A | |
| SCHEMBL8084786 | 0.78 | GCGR (0.59) | CYP1A2RAB9AALDH1A1POLBKDM4E | |
| SCHEMBL8076711 | 0.78 | MAPT (0.51) | CYP1A2RAB9ANPC1ALDH1A1POLB | |
| SCHEMBL8089979 | 0.77 | CYP1A2 (0.51) | CYP1A2RAB9ANPC1ALDH1A1POLB | |
| SCHEMBL8084106 | 0.74 | NPC1 (0.50) | CYP1A2RAB9ANPC1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |