Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | RECQL | P46063 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NSD2 | O96028 | 2/20 | 0.47 |
| ▸ | APEX1 | P27695 | 2/20 | 0.47 |
| ▸ | ALPG | P10696 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089833 | 0.87 | PPARG (0.57) | GCGRCYP1A2POLBMAPTKDM4E | |
| SCHEMBL8076795 | 0.82 | LMNA (0.45) | GCGRCYP1A2POLBMAPTKDM4E | |
| SCHEMBL8076711 | 0.82 | MAPT (0.51) | CYP1A2POLBMAPTKDM4EKMT2A | |
| SCHEMBL8076707 | 0.81 | TSHR (0.42) | GCGRCYP1A2POLBMAPTKDM4E | |
| SCHEMBL8076758 | 0.80 | CYP1A2 (0.47) | GCGRCYP1A2POLBMAPTKDM4E | |
| SCHEMBL8076747 | 0.80 | CYP1A2 (0.55) | CYP1A2POLBMAPTKDM4EKMT2A | |
| SCHEMBL8088268 | 0.80 | HSD17B10 (0.50) | CYP1A2POLBMAPTKDM4EGAA | |
| SCHEMBL8084836 | 0.79 | ALDH1A1 (0.54) | CYP1A2POLBMAPTKDM4EGAA | |
| SCHEMBL8084078 | 0.78 | CYP1A2 (0.58) | CYP1A2POLBMAPTKDM4ERECQL | |
| SCHEMBL7374498 | 0.77 | GCGR (0.59) | GCGRMAPTKDM4EGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |