Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.39 |
| ▸ | PRNP | P04156 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 8/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076742 | 0.89 | QPCT (0.41) | RXFP1PRNPKDM4EPOLBKMT2A | |
| SCHEMBL8084734 | 0.86 | HTR2C (0.44) | RXFP1KDM4EPOLBSYKCYP3A4 | |
| SCHEMBL8076714 | 0.85 | PRNP (0.34) | RXFP1PRNPKDM4EPOLBKMT2A | |
| SCHEMBL8076750 | 0.74 | BACE1 (0.39) | RXFP1PRNPKDM4EPOLBKMT2A | |
| SCHEMBL8084817 | 0.73 | HTR2C (0.43) | KDM4EKMT2ASYKCYP3A4ALDH1A1 | |
| SCHEMBL8084787 | 0.72 | KMT2A (0.39) | RXFP1PRNPKDM4EPOLBKMT2A | |
| SCHEMBL8088277 | 0.72 | PRNP (0.33) | RXFP1PRNPKDM4EPOLBKMT2A | |
| SCHEMBL10363411 | 0.71 | TERT (0.47) | KDM4EKMT2ATERTAPPSYK | |
| SCHEMBL30565763 | 0.71 | TERT (0.47) | KDM4EKMT2ATERTAPPSYK | |
| SCHEMBL1881828 | 0.69 | TERT (0.46) | KDM4ETERTAPPSYKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |