Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084817 | 0.86 | HTR2C (0.43) | HTR2CHTR2BMAPTALDH1A1TDP1 | |
| SCHEMBL8084093 | 0.86 | RXFP1 (0.39) | ALDH1A1TDP1POLBNPC1GAA | |
| SCHEMBL8076742 | 0.81 | QPCT (0.41) | ALDH1A1TDP1POLBGAAKDM1A | |
| SCHEMBL8084097 | 0.78 | HTR2C (0.48) | HTR2CHTR2BMAPTALDH1A1HTT | |
| SCHEMBL8076714 | 0.78 | PRNP (0.34) | POLBKDM4ECYP3A4RXFP1SYK | |
| SCHEMBL24430006 | 0.74 | L3MBTL1 (0.40) | MAPTALDH1A1HTTTDP1PKM | |
| SCHEMBL2816694 | 0.74 | LOXL2 (0.47) | MAPTPOLBELANEKDM4ELOXL2 | |
| SCHEMBL15922876 | 0.72 | HDAC6 (0.60) | HTR2CHTR2BMAPTALDH1A1HTT | |
| SCHEMBL8090013 | 0.70 | ALDH1A1 (0.42) | MAPTALDH1A1HTTTDP1LMNA | |
| SCHEMBL17378307 | 0.70 | ACVR1 (0.60) | HTR2CHTR2BMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |