Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084734 | 0.86 | HTR2C (0.44) | HTR2CHTR2BNPC1GAARAB9A | |
| SCHEMBL8084839 | 0.81 | AOC3 (0.34) | HTR2CHTR2BABCB1 | |
| SCHEMBL8084810 | 0.78 | CHEK2 (0.46) | SLC6A3CYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL8084097 | 0.76 | HTR2C (0.48) | HTR2CHTR2BNPC1RAB9AALDH1A1 | |
| SCHEMBL8908139 | 0.74 | HTR1A (0.47) | MAPTKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2333890 | 0.74 | HTR1A (0.47) | MAPTKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8084093 | 0.73 | RXFP1 (0.39) | NPC1GAARAB9AELANEALDH1A1 | |
| SCHEMBL8084808 | 0.73 | HTR2C (0.39) | HTR2CHTR2BRAB9AABCB1ALDH1A1 | |
| SCHEMBL12796611 | 0.72 | LOXL2 (0.53) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL8088287 | 0.72 | CYP17A1 (0.46) | HTR2CHTR2BNPC1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |