SCHEMBL808442

SCHEMBL808442

CCC=P(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.38
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
TP53 P04637 1/20 0.38
GAA P10253 1/20 0.38
PKM P14618 1/20 0.38
TSHR P16473 1/20 0.38
HSP90AA1 P07900 1/20 0.36
AOX1 Q06278 1/20 0.36
CFTR P13569 1/20 0.36
ACHE P22303 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA5A P35218 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL28241411 0.97 MEN1 (0.38) MEN1KMT2AL3MBTL1ALDH1A1LMNA
SCHEMBL27661786 0.97 MEN1 (0.38) MEN1KMT2AL3MBTL1ALDH1A1LMNA
SCHEMBL808497 0.80 MEN1 (0.41) MEN1KMT2AL3MBTL1ALDH1A1LMNA
SCHEMBL16284712 0.80 EPHX2 (0.36) MEN1KMT2AL3MBTL1ALDH1A1LMNA
SCHEMBL10665143 0.77 HSP90AA1 (0.35) MEN1KMT2AL3MBTL1ALDH1A1LMNA
SCHEMBL8190077 0.77 GAA (0.41) MEN1KMT2AALDH1A1GAAPKM
SCHEMBL7096547 0.77 ALDH1A1 (0.36) MEN1KMT2AL3MBTL1ALDH1A1LMNA
SCHEMBL4821584 0.77 MEN1 (0.42) MEN1KMT2AL3MBTL1ALDH1A1TP53
SCHEMBL14409047 0.77 AKT1 (0.43) MEN1KMT2AL3MBTL1ALDH1A1LMNA
SCHEMBL14112707 0.77 ALDH1A1 (0.40) MEN1KMT2AL3MBTL1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1678115-B1 PROCESS FOR PREPARING FUNCTIONAL GROUP-CONTAINING OLEFINIC COMPOUNDS 3M INNOVATIVE PROPERTIES CO (US) 2011-11-16 EP claimed
US-20110264206-A1 Prosthetic Valve with Sealing Members and Methods of Use Thereof MEDTRONIC, INC. (US) 2011-10-27 US claimed
JP-2007509142-A 2007-04-12 JP claimed
EP-1678115-A2 PROCESS FOR PREPARING FUNCTIONAL GROUP-CONTAINING OLEFINIC COMPOUNDS 3M Innovative Properties Company (US) 2006-07-12 EP claimed
WO-2005042462-A2 PROCESS FOR PREPARING FUNCTIONAL GROUP-CONTAINING OLEFINIC COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-05-12 WO claimed
US-6838576-B1 Process for preparing functional group-containing olefinic compounds 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-01-04 US claimed
CN-119522110-A Novel linker compounds and ligand-drug conjugates thereof 特里奥尔株式会社 2025-02-25 CN disclosed
CN-119053599-A Bicyclic compounds 安力高医药股份有限公司 2024-11-29 CN disclosed
CN-118139858-A Pyrazin-3 (2H) -one derivatives 吉利德科学公司 2024-06-04 CN disclosed
CN-116724038-A Bicyclic compounds 安力高医药股份有限公司 2023-09-08 CN disclosed
CN-107567443-B Biaryl derivatives as GPR120 agonists 株式会社LG化学 2023-04-28 CN disclosed
US-9938292-B2 Quinoline derivatives as SMO inhibitors GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) 2018-04-10 US disclosed
EP-2789602-B1 Omega-halo-2-alkynal, method for producing the same, and method for producing conjugated Z-alken-yn-yl acetate using the same SHINETSU CHEMICAL CO (JP) 2017-12-27 EP disclosed
US-5122514-A Administering renin inhibitor ABBOTT LABORATORIES (US) 1992-06-16 US disclosed
WO-1991016031-A1 PSORIASIS TREATMENT ABBOTT LABORATORIES (US) 1991-10-31 WO disclosed
EP-0290145-A1 Aliphatic carboxamides ZENECA INC. (US) 1988-11-09 EP disclosed
US-4715884-A MONOCOTYLEDONOUS WEEDS IN DICOTYLEDONOUS CROPS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-12-29 US disclosed
US-4659362-A Herbicidal 5-pyrimidylcyclohexan-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1987-04-21 US disclosed
EP-0102823-A2 Herbicidal cyclohexane-1,3-dione derivatives ICI AUSTRALIA LIMITED (AU) 1984-03-14 EP disclosed
US-4391827-A 3-(2-Hydroxy-4-(substituted)phenyl)-cycloalkanone and cycloalkanol analgesic agents and intermediates therefor PFIZER INC. (US) 1983-07-05 US disclosed