Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523648 | 0.83 | GAA (0.45) | GAAHSP90AA1CFTRCA2CA4 | |
| SCHEMBL808442 | 0.77 | MEN1 (0.39) | GAAHSP90AA1CFTRCA2CA4 | |
| Bromide SCHEMBL28241411 | 0.75 | MEN1 (0.38) | GAAHSP90AA1CFTRCA2CA4 | |
| SCHEMBL27661786 | 0.75 | MEN1 (0.38) | GAAHSP90AA1CFTRCA2CA4 | |
| SCHEMBL10665143 | 0.75 | HSP90AA1 (0.35) | GAAHSP90AA1CFTRCA2CA4 | |
| SCHEMBL7096547 | 0.75 | ALDH1A1 (0.36) | GAAHSP90AA1CFTRCA2CA4 | |
| SCHEMBL3115111 | 0.75 | USP2 (0.47) | GAAHSP90AA1CFTRCA2CA4 | |
| SCHEMBL27728842 | 0.75 | HSP90AA1 (0.44) | GAAHSP90AA1CFTRCA2CA4 | |
| SCHEMBL808497 | 0.73 | MEN1 (0.41) | GAAHSP90AA1TSHRALDH1A1MEN1 | |
| Bromide SCHEMBL11501984 | 0.73 | ALDH1A1 (0.35) | GAAHSP90AA1CFTRCA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230663-A1 | PROCESS FOR THE PREPARATION OF DONEPEZIL HYDROCHLORIDE | ALEMBIC LIMITED (IN) | 2011-09-22 | — | — | US | disclosed |
| US-6043270-A | ANTIINFLAMMATORY AGENTS | PROCYON PHARMACEUTICALS, INC. (US) | 2000-03-28 | — | — | US | disclosed |
| US-5962498-A | Protein kinase C modulators. C. indolactam structural-types with anti-inflammatory activity | PROCYON PHARMACEUTICALS, INC. (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0553107-B1 | PROTEIN KINASE C MODULATORS WITH ANTI-INFLAMMATORY AND ANTIVIRAL ACTIVITY | PROCYON PHARM INC (US) | 1999-09-29 | — | — | EP | disclosed |
| US-5955501-A | DERIVED FROM PHORBOIDS OF THE DITERPENE- AND BENZOLACTAM-CLASSES. | PROCYON PHARMACEUTICALS, INC. (US) | 1999-09-21 | — | — | US | disclosed |
| US-5891870-A | ANTIINFLAMMATORY AGENTS USING BENZODITERPENES AND BENZOLACTAMS | PROCYON PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |
| US-5891906-A | Polyacetate-derived phorboids having anti-inflammatory and other uses | PROCYON PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |
| US-5886017-A | Protein kinase C modulators. E. | PROCYON PHARMACEUTICALS, INC. (US) | 1999-03-23 | — | — | US | disclosed |
| US-5886019-A | REPLACEMENT OF HYDROXYMETHYL OR-ETHYL GROUP ON TRICYCLIC AROMATIC HETEROCYCLIC COMPOUNDS HAVING INDOLE, INDENE, BENZOFURAN OR BENZOTHIOPHENE SKELETON; ANTIINFLAMMATORY, ANTIVIRAL | PROCYON PHARMACEUTICALS, INC. (US) | 1999-03-23 | — | — | US | disclosed |
| US-5750568-A | DITERPENE PHORBOIDS | PROCYON PHARMACEUTICALS, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5716968-A | ANTIINFLAMMATORY AGENTS; VIRICIDE | PROCYON PHARMACEUTICALS, INC. (US) | 1998-02-10 | — | — | US | disclosed |
| EP-0455271-B1 | Anti-inflammatory compositions | PROCYON PHARM INC (US) | 1997-08-20 | — | — | EP | disclosed |
| US-5643948-A | ANTIINFLAMMATORY, ANTICANCER | PROCYON PHARMACEUTICALS, INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5145842-A | Protein kinase c. modulators. d. | ALDER RESEARCH CENTER LIMITED PARTNERSHIP (US) | 1992-09-08 | — | — | US | disclosed |
| WO-1992002484-A1 | PROTEIN KINASE C MODULATORS WITH ANTI-INFLAMMATORY AND ANTIVIRAL ACTIVITY | ALDER RESEARCH CENTER LIMITED PARTNERSHIP (US) | 1992-02-20 | — | — | WO | disclosed |
| US-5068325-A | Dopaminergic systems as hypotensives, sedatives, antitussives and/or antiphlogistics | KARL THOMAE GMBH (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0455271-A2 | Anti-inflammatory compositions | PROCYON PHARMACEUTICALS, INC. (US) | 1991-11-06 | — | — | EP | disclosed |
| EP-0310622-A1 | ANTI-INFLAMMATORY COMPOSITIONS. | ALDER RES CENTER CORP (US) | 1989-04-12 | — | — | EP | disclosed |
| WO-1987007599-A2 | ANTI-INFLAMMATORY COMPOSITIONS | ALDER RESEARCH CENTER CORPORATION (US) | 1987-12-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230663-A1 | PROCESS FOR THE PREPARATION OF DONEPEZIL HYDROCHLORIDE | BCHE, ACHE, PSEN1 | GAA 157/4885HSP90AA1 4317/4885CFTR 4171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.