Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL808442 | 0.77 | MEN1 (0.39) | ALDH1A1MEN1KMT2AGAATSHR | |
| Bromide SCHEMBL28241411 | 0.75 | MEN1 (0.38) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL10665143 | 0.75 | HSP90AA1 (0.35) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL27661786 | 0.75 | MEN1 (0.38) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL8190077 | 0.75 | GAA (0.41) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL9802194 | 0.75 | AOX1 (0.47) | ALDH1A1MEN1KMT2AGAATSHR | |
| Bromide SCHEMBL11501984 | 0.73 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL7523648 | 0.73 | GAA (0.45) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL27728843 | 0.73 | AOX1 (0.42) | ALDH1A1MEN1KMT2AGAATSHR | |
| SCHEMBL808497 | 0.73 | MEN1 (0.41) | ALDH1A1MEN1KMT2AGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307579-A2 | BIO-INTERMEDIATES FOR USE IN THE CHEMICAL SYNTHESIS OF POLYKETIDES | Kosan Biosciences, Inc. (US) | 2003-05-07 | — | — | EP | disclosed |
| WO-2002012534-A2 | BIO-INTERMEDIATES FOR USE IN THE CHEMICAL SYNTHESIS OF POLYKETIDES | KOSAN BIOSCIENCES, INC. (US) | 2002-02-14 | — | — | WO | disclosed |