SCHEMBL8084623

SCHEMBL8084623

C=C(C)C(=O)OC(C)(C)CN.c1ccc(B(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
TDP1 Q9NUW8 2/20 0.32
ATM Q13315 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
KDM4E B2RXH2 1/20 0.30
KMT2A Q03164 1/20 0.30
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Chloromethyl)Benzene SCHEMBL252406 0.82 ELANE (0.35) ELANECYP2C19HIF1AATMALDH1A1
SCHEMBL735183 0.81 ALDH1A1 (0.41) TDP1ALDH1A1KDM4E
Chloromethane SCHEMBL253218 0.79 ALDH1A1 (0.39) TDP1ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL327263 0.78 ALDH1A1 (0.38) TDP1ALDH1A1
SCHEMBL5531274 0.74 CTSK (0.44) ELANECYP2C19HIF1ATAAR1ALDH1A1
SCHEMBL3180129 0.73 CYP2C19 (0.46) ELANECYP2C19HIF1ATDP1ATM
SCHEMBL4148102 0.72 HSD11B1 (0.46) CYP2C19ALDH1A1MAPTKMT2APOLB
Acrylamide SCHEMBL11512778 0.72 ALDH1A1 (0.38) TDP1ALDH1A1
Sulfuric Acid Dimethyl Ester SCHEMBL7646730 0.71 ALDH1A1 (0.36) ALDH1A1
SCHEMBL2574845 0.71 ALDH1A1 (0.41) ELANECYP2C19HIF1ATDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000143673-A TRIARYLBORANE-AMINE COMPOUND, TRIARYLBORANE-AMINE- BASED (CO)POLYMER AND UNDERWATER ANTIFOULING AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT HOKKO CHEM IND CO LTD 2000-05-26 JP disclosed