Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | ESRRB | O95718 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESRRA | P11474 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | DTYMK | P23919 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084900 | 0.87 | SMN1; SMN2 (0.46) | GBA1ACHELMNAKITESRRB | |
| SCHEMBL8089838 | 0.86 | ALDH1A1 (0.35) | LMNAMEN1ALDH1A1MAPTTSHR | |
| SCHEMBL8084675 | 0.84 | SMN1; SMN2 (0.44) | GBA1ACHELMNAESRRBESR1 | |
| SCHEMBL8088233 | 0.83 | RAB9A (0.42) | LMNAKITMEN1ALDH1A1MAPT | |
| SCHEMBL8076743 | 0.81 | CHRM2 (0.41) | GBA1ACHEDTYMKCNR2CHRM2 | |
| SCHEMBL8076724 | 0.80 | NAMPT (0.46) | LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8088289 | 0.77 | IDO1 (0.42) | LMNAKITMEN1ALDH1A1MAPT | |
| SCHEMBL8084112 | 0.77 | MAPT (0.48) | LMNACHRM1ALDH1A1MAPTKMT2A | |
| SCHEMBL8089904 | 0.76 | LMNA (0.51) | LMNAIDEMEN1ALDH1A1MAPT | |
| SCHEMBL2422976 | 0.76 | PDGFRB (0.55) | GBA1ACHEKITSMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |