Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | ESRRB | O95718 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | ESRRG | P62508 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084675 | 0.97 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL8084112 | 0.90 | MAPT (0.48) | SMN1; SMN2KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL8089904 | 0.89 | LMNA (0.51) | SMN1; SMN2MEN1KMT2AHTTNPSR1 | |
| SCHEMBL8076752 | 0.88 | MEN1 (0.42) | SMN1; SMN2MEN1KMT2AHTTNPSR1 | |
| SCHEMBL8088289 | 0.88 | IDO1 (0.42) | SMN1; SMN2MEN1KMT2ACYP2C19HTT | |
| SCHEMBL8084765 | 0.87 | GBA1 (0.44) | SMN1; SMN2MEN1KMT2AHTTNPSR1 | |
| SCHEMBL8084676 | 0.87 | CCNC (0.46) | SMN1; SMN2NPSR1MAPTLMNANPC1 | |
| SCHEMBL8084719 | 0.86 | ALOX15 (0.49) | SMN1; SMN2CYP2C19NPSR1MAPTLMNA | |
| SCHEMBL8076743 | 0.86 | CHRM2 (0.41) | GBA1ACHE | |
| SCHEMBL8084897 | 0.86 | LMNA (0.42) | SMN1; SMN2MEN1KMT2AHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |