Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CDC7 | O00311 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089902 | 0.85 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL8088268 | 0.83 | HSD17B10 (0.50) | ALDH1A1SMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL8084741 | 0.81 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL8084757 | 0.81 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL8084879 | 0.80 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL8084786 | 0.79 | GCGR (0.59) | ALDH1A1RAB9AKMT2AKDM4EHPGD | |
| SCHEMBL8084739 | 0.79 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL8084097 | 0.79 | HTR2C (0.48) | ALDH1A1SMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL8090035 | 0.79 | SMN1; SMN2 (0.54) | ALDH1A1SMN1; SMN2RAB9AHPGDGAA | |
| SCHEMBL8076747 | 0.79 | CYP1A2 (0.55) | ALDH1A1SMN1; SMN2RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |