Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575498 | 0.91 | CYP1A2 (0.53) | LMNAL3MBTL1GLAKMT2AMEN1 | |
| SCHEMBL898712 | 0.89 | LMNA (0.58) | LMNAKMT2AMEN1MAPTALDH1A1 | |
| Butane SCHEMBL1395551 | 0.86 | KDM4E (0.47) | LMNAL3MBTL1GLAKMT2AMEN1 | |
| SCHEMBL9873999 | 0.85 | NPC1 (0.48) | LMNAL3MBTL1GLAKMT2AMEN1 | |
| SCHEMBL10962581 | 0.84 | NPC1 (0.50) | LMNAL3MBTL1GLAKMT2AMEN1 | |
| SCHEMBL8084797 | 0.84 | NPC1 (0.47) | LMNAL3MBTL1GLAKMT2AMEN1 | |
| SCHEMBL6577955 | 0.83 | KMT2A (0.47) | LMNAL3MBTL1GLAKMT2AMEN1 | |
| 1,2-Dipropoxybenzene SCHEMBL578657 | 0.82 | CYP1A2 (0.56) | LMNAL3MBTL1KMT2AMEN1NPC1 | |
| 1,2-Dipropoxybenzene SCHEMBL29428926 | 0.82 | CYP1A2 (0.56) | LMNAL3MBTL1KMT2AMEN1NPC1 | |
| SCHEMBL28027916 | 0.81 | L3MBTL1 (0.73) | LMNAL3MBTL1GLAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983609-A | Anticancer agents | OTSUKA PHARMACEUTICAL (JP) | 1991-01-08 | — | — | US | disclosed |
| US-4864021-A | ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0323441-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0180897-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |