Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486872 | 0.96 | ALDH1A1 (0.61) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL7146204 | 0.96 | ALDH1A1 (0.61) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL900809 | 0.96 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL8091203 | 0.96 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL11085391 | 0.96 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL10625481 | 0.96 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL8761655 | 0.96 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL3637 | 0.96 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL10635593 | 0.96 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| Aspartame SCHEMBL216238 | 0.96 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526854-B1 | Method for recovery of alpha-L-aspartyl-L-phenylalanine methyl ester, L-phenylalanine and l-aspartic acid | AJINOMOTO KK (JP) | 1997-05-02 | — | — | EP | claimed |
| US-5347035-A | Purification | TOSOH CORPORATION (JP) | 1994-09-13 | — | — | US | claimed |
| US-5304671-A | Solid-liquid separation of suspension; no desalting; precipitation of acid salt; neutralization; hydrolysis | AJINOMOTO CO., INC. (JP) | 1994-04-19 | — | — | US | claimed |
| EP-0526854-A2 | Method for recovery of alpha-L-aspartyl-L-phenylalanine methyl ester, L-phenylalanine and l-aspartic acid | Ajinomoto Co., Inc. (JP) | 1993-02-10 | — | — | EP | claimed |
| JP-5286994-A | — | — | None | — | — | JP | disclosed |
| EP-0510552-B2 | Preparation process of alpha-aspartyl-L-phenylalanine methyl ester | MITSUI TOATSU CHEMICALS (JP) | 2000-11-15 | — | — | EP | disclosed |
| US-5424477-A | Preparation process of α-aspartyl-L-phenylalanine methyl ester | MITSUI TOATSU CHEMICALS INCORPORATED (JP) | 1995-06-13 | — | — | US | disclosed |
| US-5347035-A | Purification | TOSOH CORPORATION (JP) | 1994-09-13 | — | — | US | disclosed |
| US-5347035-A | Purification | TOSOH CORPORATION (JP) | 1994-09-13 | — | — | US | disclosed |
| JP-H05286994-A | METHOD FOR CRYSTALLIZING ALPHA-L-ASPARTYL-LPHENYLALANINE METHYL ESTER | TOSOH CORP | 1993-11-02 | — | — | JP | disclosed |
| EP-0510552-A1 | Preparation process of alpha-aspartyl-L-phenylalanine methyl ester | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-10-28 | — | — | EP | disclosed |
| EP-0099585-B1 | PROCESS FOR PRODUCING AN ADDITION COMPOUND OF A DIPEPTIDE ESTER AND AN AMINO ACID ESTER | TOYO SODA MANUFACTURING CO., LTD. (JP) | 1987-11-04 | — | — | EP | disclosed |
| US-4521514-A | Process for producing an addition compound of a dipeptide ester and an amino acid ester | TOYO SODA MANUFACTURING CO., LTD. (JP) | 1985-06-04 | — | — | US | disclosed |
| EP-0099585-A1 | Process for producing an addition compound of a dipeptide ester and an amino acid ester | TOYO SODA MANUFACTURING CO., LTD. (JP) | 1984-02-01 | — | — | EP | disclosed |
| US-4017472-A | Process for isolation of aspartyl dipeptide esters | G. D. SEARLE & CO. (US) | 1977-04-12 | — | — | US | disclosed |