Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29561496 | 1.00 | EPHX1 (0.42) | EPHX1TRPM8TRPA1ALDH1A1CYP19A1 | |
| SCHEMBL16041029 | 0.92 | EPHX1 (0.38) | EPHX1TRPM8TRPA1ALDH1A1CYP19A1 | |
| SCHEMBL583663 | 0.87 | EPHX1 (0.41) | EPHX1TRPM8TRPA1ALDH1A1CYP19A1 | |
| SCHEMBL8375721 | 0.85 | TRPM8 (0.47) | EPHX1TRPM8TRPA1ALDH1A1CYP19A1 | |
| SCHEMBL30772345 | 0.84 | EPHX1 (0.38) | EPHX1TRPM8TRPA1ALDH1A1CYP19A1 | |
| SCHEMBL5690453 | 0.80 | EPHX1 (0.47) | EPHX1TRPM8TRPA1ALDH1A1CYP19A1 | |
| SCHEMBL583712 | 0.80 | EPHX1 (0.47) | EPHX1TRPM8TRPA1ALDH1A1CYP19A1 | |
| SCHEMBL18280698 | 0.75 | EPHX1 (0.45) | EPHX1TRPM8TRPA1ALDH1A1CYP19A1 | |
| SCHEMBL19209892 | 0.74 | EPHX1 (0.47) | EPHX1TRPM8TRPA1ALDH1A1CYP19A1 | |
| SCHEMBL19753622 | 0.74 | EPHX1 (0.55) | EPHX1TRPM8TRPA1ALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014198366-A1 | GLOVE WITH A COOLING EFFECT | CARL FREUDENBERG KG (DE) | 2014-12-18 | — | — | WO | claimed |
| EP-2276356-B1 | WARMING SENSATE COMPOSITION | FIRMENICH & CIE (CH) | 2013-06-19 | — | — | EP | claimed |
| EP-2276356-A1 | WARMING SENSATE COMPOSITION | Firmenich S.A. (CH) | 2011-01-26 | — | — | EP | claimed |
| US-20110015227-A1 | WARMING SENSATE COMPOSITION | FIRMENICH SA (CH) | 2011-01-20 | — | — | US | claimed |
| JP-4608499-B2 | — | — | 2011-01-12 | — | — | JP | claimed |
| WO-2009127992-A1 | WARMING SENSATE COMPOSITION | FIRMENICH SA (CH) | 2009-10-22 | — | — | WO | claimed |
| EP-1874132-A1 | HOT FLAVOUR AND SKIN SENSATION COMPOSITION | FIRMENICH SA (CH) | 2008-01-09 | — | — | EP | claimed |
| US-20080000614-A1 | HOT FLAVOR AND SKIN SENSATION COMPOSITION | FIRMENICH SA (CH) | 2008-01-03 | — | — | US | claimed |
| JP-2007516316-A | — | — | 2007-06-21 | — | — | JP | claimed |
| WO-2006109241-A1 | HOT FLAVOUR AND SKIN SENSATION COMPOSITION | FIRMENICH SA (CH) | 2006-10-19 | — | — | WO | claimed |
| EP-1682641-A1 | FLAVOR INGREDIENTS FOR COOLING PREPARATIONS | FIRMENICH SA (CH) | 2006-07-26 | — | — | EP | claimed |
| WO-2005042680-A1 | FLAVOR INGREDIENTS FOR COOLING PREPARATIONS | FIRMENICH SA (CH) | 2005-05-12 | — | — | WO | claimed |
| WO-2014198366-A1 | GLOVE WITH A COOLING EFFECT | CARL FREUDENBERG KG (DE) | 2014-12-18 | — | — | WO | disclosed |
| WO-2011056748-A2 | ORAL COMPOSITIONS FOR TREATMENT OF DRY MOUTH | THE PROCTER & GAMBLE COMPANY (US) | 2011-05-12 | — | — | WO | disclosed |
| WO-2009065239-A1 | COMPOSITIONS AND THEIR USE | GIVAUDAN SA (CH) | 2009-05-28 | — | — | WO | disclosed |
| EP-1874132-A1 | HOT FLAVOUR AND SKIN SENSATION COMPOSITION | FIRMENICH SA (CH) | 2008-01-09 | — | — | EP | disclosed |
| US-20060249167-A1 | Flavor ingredients for cooling preparations | FIRMENICH SA (CH) | 2006-11-09 | — | — | US | disclosed |
| WO-2006109241-A1 | HOT FLAVOUR AND SKIN SENSATION COMPOSITION | FIRMENICH SA (CH) | 2006-10-19 | — | — | WO | disclosed |
| EP-1682641-A1 | FLAVOR INGREDIENTS FOR COOLING PREPARATIONS | FIRMENICH SA (CH) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005042680-A1 | FLAVOR INGREDIENTS FOR COOLING PREPARATIONS | FIRMENICH SA (CH) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015227-A1 | WARMING SENSATE COMPOSITION | TAS1R3, TAS2R30, TAS2R50 | EPHX1 3988/4885TRPM8 76/4885TRPA1 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.