Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30772345 | 0.88 | EPHX1 (0.38) | EPHX1TRPM8TRPA1ALDH1A1TRPV1 | |
| SCHEMBL29561496 | 0.87 | EPHX1 (0.42) | EPHX1TRPM8TRPA1ALDH1A1TRPV1 | |
| SCHEMBL80852 | 0.87 | EPHX1 (0.42) | EPHX1TRPM8TRPA1ALDH1A1TRPV1 | |
| SCHEMBL16041029 | 0.85 | EPHX1 (0.38) | EPHX1TRPM8TRPA1ALDH1A1TRPV1 | |
| SCHEMBL8375721 | 0.84 | TRPM8 (0.47) | EPHX1TRPM8TRPA1ALDH1A1TRPV1 | |
| SCHEMBL583712 | 0.82 | EPHX1 (0.47) | EPHX1TRPM8TRPA1ALDH1A1TRPV1 | |
| SCHEMBL5690453 | 0.82 | EPHX1 (0.47) | EPHX1TRPM8TRPA1ALDH1A1TRPV1 | |
| SCHEMBL9951715 | 0.72 | EPHX1 (0.53) | EPHX1TRPM8TRPA1TRPV1KCNA5 | |
| SCHEMBL1030886 | 0.72 | EPHX1 (0.53) | EPHX1TRPM8TRPA1ALDH1A1TRPV1 | |
| SCHEMBL3274993 | 0.72 | EPHX1 (0.53) | EPHX1TRPM8TRPA1TRPV1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 603 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240058243-A1 | A METHOD FOR FIGHTING MICROORGANISMS USING MENTHOL DERIVATIVES | SYMRISE AG (DE) | 2024-02-22 | — | — | US | claimed |
| EP-4259287-A1 | A METHOD FOR FIGHTING MICROORGANISMS USING MENTHOL DERIVATIVES | Symrise AG (DE) | 2023-10-18 | — | — | EP | claimed |
| EP-3081207-B1 | USE OF A LIPOSOME COMPOSITION | SYMRISE AG (DE) | 2022-09-21 | — | — | EP | claimed |
| WO-2022122144-A1 | A METHOD FOR FIGHTING MICROORGANISMS USING MENTHOL DERIVATIVES | SYMRISE AG (DE) | 2022-06-16 | — | — | WO | claimed |
| EP-3687311-A1 | AMIDES FOR GENERATING A TRIGEMINAL EFFECT | Symrise AG (DE) | 2020-08-05 | — | — | EP | claimed |
| EP-3142499-B1 | HOMOVANILLIC ACID ESTERS, IN PARTICULAR FOR ACHIEVING AN IMPRESSION OF HEAT AND/OR SPICINESS | SYMRISE AG (DE) | 2019-10-30 | — | — | EP | claimed |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2019-08-27 | — | — | US | claimed |
| US-20190099342-A1 | COOLING PRODUCT | SYMRISE AG (DE) | 2019-04-04 | — | — | US | claimed |
| WO-2019063069-A1 | AMIDES FOR GENERATING A TRIGEMINAL EFFECT | SYMRISE AG (DE) | 2019-04-04 | — | — | WO | claimed |
| EP-3142499-A1 | HOMOVANILLIC ESTER, MORE PARTICULARLY FOR ACHIEVING AN IMPRESSION OF HEAT AND/OR SPICINESS | Symrise AG (DE) | 2017-03-22 | — | — | EP | claimed |
| WO-2016166038-A1 | WHITENING COMPOSITIONS | SYMRISE AG (DE) | 2016-10-20 | — | — | WO | claimed |
| EP-3081207-A1 | WHITENING COMPOSITIONS | Symrise AG (DE) | 2016-10-19 | — | — | EP | claimed |
| WO-2015158677-A1 | HOMOVANILLIC ESTER, MORE PARTICULARLY FOR ACHIEVING AN IMPRESSION OF HEAT AND/OR SPICINESS | SYMRISE AG (DE) | 2015-10-22 | — | — | WO | claimed |
| EP-2932858-A1 | Homovanillic acid esters, in particular for achieving an impression of heat and/or spiciness | Symrise AG (DE) | 2015-10-21 | — | — | EP | claimed |
| EP-2008530-B1 | Aroma composition for reducing or suppressing unwanted bitter and astringent impressions | SYMRISE AG (DE) | 2011-01-19 | — | — | EP | claimed |
| EP-2008530-A1 | Aroma composition for reducing or suppressing unwanted bitter and astringent impressions | Symrise GmbH & Co. KG (DE) | 2008-12-31 | — | — | EP | claimed |
| EP-1541039-B1 | Flavour composition comprising cubebol and a further refreshing agent | FIRMENICH & CIE (CH) | 2008-01-02 | — | — | EP | claimed |
| EP-4103144-B1 | COMPOSITIONS COMPRISING UV-FILTERS AND ONE OR MORE (BIO)-ALKANEDIOLS | SYMRISE AG (DE) | 2026-05-27 | — | — | EP | disclosed |
| EP-1529095-A1 | CARVONE ACETALS USED AS FLAVOURINGS | Symrise GmbH & Co. KG (DE) | 2005-05-11 | — | — | EP | disclosed |
| WO-2004015044-A1 | CARVONE ACETALS USED AS FLAVOURINGS | SYMRISE GMBH & CO. KG (DE) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190099342-A1 | COOLING PRODUCT | TRPA1, TRPV2, NISCH | EPHX1 1636/4885TRPM8 44/4885TRPA1 1/4885 |
| US-20240058243-A1 | A METHOD FOR FIGHTING MICROORGANISMS USING MENTHOL DERIVATIVES | MGLL, GCDH, GK | EPHX1 1246/4885TRPM8 84/4885TRPA1 187/4885 |
| US-10392371-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM4, TRPM6 | EPHX1 4010/4885TRPM8 1/4885TRPA1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.