Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 12/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6946126 | 0.76 | SLC6A4 (0.70) | SLC6A2SLC6A4SLC6A3CYP2D6MEN1 | |
| SCHEMBL5709376 | 0.76 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3CYP2D6CYP2C9 | |
| SCHEMBL14596264 | 0.71 | HTR2A (0.37) | SLC6A2SLC6A4ADRB1HTR1AADRA2A | |
| SCHEMBL28129775 | 0.70 | SIGMAR1 (0.55) | HTR2AHTR2CADRA1AHTR2BSIGMAR1 | |
| SCHEMBL8938880 | 0.70 | IGF1R (0.54) | CYP2C9CYP3A4DRD2ADRA2CMTOR | |
| SCHEMBL5450678 | 0.69 | ACHE (0.51) | HTR1AHTR2A | |
| SCHEMBL2056277 | 0.69 | ALDH1A1 (0.50) | SLC6A2SLC6A4SLC6A3CYP2D6KMT2A | |
| SCHEMBL29757864 | 0.68 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3CYP2D6MEN1 | |
| SCHEMBL5029704 | 0.68 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3CYP2D6MEN1 | |
| SCHEMBL8238524 | 0.68 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044184-A1 | SYNTHESIS OF 3-ARYL-1-INDANAMINES | Pharm-Eco Laboratoires, Incorporated (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999035119-A1 | SYNTHESIS OF 3-ARYL-1-INDANAMINES | PHARM-ECO LABORATORIES, INC. (US) | 1999-07-15 | — | — | WO | disclosed |