Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28736730 | 0.82 | MAPT (0.48) | MAPTNPC1RAB9AGAAL3MBTL1 | |
| SCHEMBL21443321 | 0.77 | RAB9A (0.56) | MAPTNPC1RAB9AGAAL3MBTL1 | |
| SCHEMBL29067521 | 0.77 | TGM2 (0.46) | MAPTNPC1RAB9AGAAL3MBTL1 | |
| SCHEMBL28946714 | 0.77 | FPR2 (0.51) | MAPTNPC1RAB9AGAAL3MBTL1 | |
| SCHEMBL28946713 | 0.77 | FPR2 (0.51) | MAPTNPC1RAB9AGAAL3MBTL1 | |
| SCHEMBL10771680 | 0.75 | ALDH1A1 (0.56) | MAPTNPC1RAB9AGAAL3MBTL1 | |
| SCHEMBL28635453 | 0.74 | ALDH1A1 (0.50) | MAPTNPC1RAB9AGAAL3MBTL1 | |
| SCHEMBL3145055 | 0.74 | MAPT (0.53) | MAPTNPC1RAB9AGAAL3MBTL1 | |
| SCHEMBL3141547 | 0.74 | ALDH1A1 (0.60) | MAPTNPC1RAB9AGAAL3MBTL1 | |
| SCHEMBL633443 | 0.74 | ALDH1A1 (0.60) | MAPTNPC1RAB9AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000256287-A | 1,2-DIAMINODIOL COMPOUND, ITS INTERMEDIATE AND THEIR PRODUCTION | SUMITOMO CHEM CO LTD | 2000-09-19 | — | — | JP | disclosed |