Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 1/20 | 0.35 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 2/20 | 0.31 |
| ▸ | CALCA | P06881 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27463844 | 0.85 | KDM4E (0.38) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8183610 | 0.77 | MEN1 (0.32) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8086903 | 0.75 | KDM4E (0.37) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8498410 | 0.74 | NQO2 (0.32) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL27487605 | 0.73 | SLC13A5 (0.33) | KDM4E | |
| SCHEMBL8085969 | 0.72 | NQO2 (0.40) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL23575853 | 0.72 | MTNR1A (0.44) | VSIRMTNR1AMTNR1BKDM4EMEN1 | |
| SCHEMBL8078878 | 0.72 | GPR35 (0.41) | KDM4EMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5973164 | 0.71 | NQO2 (0.41) | ALDH1A1 | |
| SCHEMBL5201034 | 0.70 | VSIR (0.38) | LATS1VSIRMTNR1AMTNR1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1137886-C | 2,3-dioxo-1,2,3,4-tetrahydro-quinoyxalinyl derivatives | ��˹��ŵ�� | 2004-02-11 | — | — | CN | disclosed |
| US-6080743-A | AS CHEMICAL INTERMEIDATES FOR PREPARING DRUGS | NOVARTIS AG (CH) | 2000-06-27 | — | — | US | disclosed |
| CN-1193968-A | 2,3-dioxo-1,2,3,4-tetrahydro-quinoyxalinyl derivatives | NOVARTIS AG (CH) | 1998-09-23 | — | — | CN | disclosed |
| EP-0853617-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | Novartis AG (CH) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997008155-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | disclosed |