Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CFD | P00746 | 2/20 | 0.43 |
| ▸ | F11 | P03951 | 2/20 | 0.43 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | MMP16 | P51512 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24200105 | 1.00 | CXCL8 (0.50) | CXCL8L3MBTL1AKR1B1CHRM1CFD | |
| SCHEMBL10343471 | 0.86 | MTNR1A (0.39) | CXCL8L3MBTL1MAPTMTNR1AMTNR1B | |
| SCHEMBL3941649 | 0.85 | CXCL8 (0.54) | CXCL8L3MBTL1AKR1B1CHRM1CFD | |
| SCHEMBL23229157 | 0.85 | CXCL8 (0.54) | CXCL8L3MBTL1AKR1B1CHRM1CFD | |
| SCHEMBL19840604 | 0.84 | MTNR1A (0.44) | L3MBTL1MAPTMTNR1AMTNR1B | |
| SCHEMBL21455171 | 0.84 | CXCL8 (0.48) | CXCL8L3MBTL1AKR1B1CHRM1CFD | |
| SCHEMBL8998039 | 0.83 | CXCL8 (0.47) | CXCL8L3MBTL1AKR1B1CHRM1CFD | |
| SCHEMBL23425588 | 0.83 | TBXAS1 (0.47) | L3MBTL1MAPT | |
| SCHEMBL23656617 | 0.83 | TSHR (0.51) | L3MBTL1MAPTTDP1MTNR1AMTNR1B | |
| SCHEMBL23241478 | 0.83 | TBXAS1 (0.47) | L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3939658-A1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | Biocryst Pharmaceuticals, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |
| EP-0758013-B1 | Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display | NIPPON OIL CO LTD (JP) | 2000-10-11 | — | — | EP | disclosed |
| US-5855971-A | Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film | NIPPON OIL COMPANY, LIMITED (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0758013-A1 | Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display | NIPPON OIL COMPANY, LIMITED (JP) | 1997-02-12 | — | — | EP | disclosed |