Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.38 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9265198 | 0.85 | CXCL8 (0.42) | CXCL8L3MBTL1AKR1B1ALDH1A1KDM4E | |
| SCHEMBL24200105 | 0.83 | CXCL8 (0.50) | CXCL8L3MBTL1AKR1B1CHRM1CFD | |
| SCHEMBL8086435 | 0.83 | CXCL8 (0.50) | CXCL8L3MBTL1AKR1B1CHRM1CFD | |
| SCHEMBL3941649 | 0.81 | CXCL8 (0.54) | CXCL8L3MBTL1AKR1B1ALDH1A1KDM4E | |
| SCHEMBL23229157 | 0.81 | CXCL8 (0.54) | CXCL8L3MBTL1AKR1B1CHRM1CFD | |
| SCHEMBL4565147 | 0.77 | LTB4R (0.54) | CXCL8L3MBTL1AKR1B1CHRM1CFD | |
| SCHEMBL4565149 | 0.77 | LTB4R (0.54) | CXCL8L3MBTL1AKR1B1CHRM1CFD | |
| SCHEMBL8998082 | 0.76 | POLB (0.52) | L3MBTL1 | |
| SCHEMBL21455171 | 0.75 | CXCL8 (0.48) | CXCL8L3MBTL1AKR1B1CHRM1CFD | |
| SCHEMBL3135922 | 0.74 | CXCL8 (0.58) | CXCL8L3MBTL1AKR1B1CHRM1CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5484942-A | Thiopyranopyrrole derivatives | RHONE-POULENC RORER S.A. (FR) | 1996-01-16 | — | — | US | disclosed |