Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1290446 | 0.78 | TSHR (0.50) | SMN1; SMN2CYP3A4TSHRPARP1SIRT2 | |
| SCHEMBL8087953 | 0.77 | MAOA (0.42) | SMN1; SMN2CYP3A4GPR84TSHRKMT2A | |
| SCHEMBL10785469 | 0.71 | RARB (0.54) | TSHRKMT2AALDH1A1MAPT | |
| SCHEMBL12075502 | 0.70 | GPR84 (0.41) | CYP3A4GPR84TSHRPDE4APDE4B | |
| SCHEMBL4000998 | 0.69 | ALDH1A1 (0.39) | CYP3A4GPR84TSHRKMT2ALMNA | |
| SCHEMBL5183969 | 0.68 | ESR1 (0.50) | CYP3A4LMNAALDH1A1 | |
| SCHEMBL4934938 | 0.67 | MAOA (0.48) | SMN1; SMN2PKMMAPT | |
| SCHEMBL2012347 | 0.67 | SIGMAR1 (0.44) | TSHRKMT2ALMNAALDH1A1 | |
| SCHEMBL17277606 | 0.67 | PARP10 (0.42) | GPR84TSHRPARP1MAPTPDE4A | |
| SCHEMBL9356418 | 0.66 | IGF1R (0.47) | CYP3A4KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013760-A | COPOLYMER HAVING SUCCINYL DICARBOXYCYCLOHEXENE DERIVATIVE AND DIAMINOBENZAMIDE DERIVATIVE UNITS; PROCESSABILITY | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2000-01-11 | — | — | US | disclosed |