SCHEMBL8086738

SCHEMBL8086738

CCn1c2ccccc2c(=O)c2cc(Cl)ccc21

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.72
PTGER4 P35408 2/20 0.56
MAPT P10636 5/20 0.52
TDP1 Q9NUW8 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TP53 P04637 3/20 0.52
KDM4E B2RXH2 3/20 0.51
HPGD P15428 2/20 0.51
MAPK1 P28482 2/20 0.51
HSD17B10 Q99714 2/20 0.51
LMNA P02545 2/20 0.51
P2RX4 Q99571 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
HTT P42858 1/20 0.50
HBB P68871 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11391828 0.91 ALDH1A1 (0.72) ALDH1A1PTGER4MAPTTDP1CYP1A2
SCHEMBL20291531 0.88 ALDH1A1 (0.54) ALDH1A1MAPTTP53HPGDP2RX4
SCHEMBL29660662 0.88 ALDH1A1 (0.54) ALDH1A1MAPTTP53HPGDP2RX4
SCHEMBL29643271 0.87 MAPT (0.65) ALDH1A1PTGER4MAPTTDP1CYP1A2
SCHEMBL1921288 0.87 MAPT (0.65) ALDH1A1PTGER4MAPTTDP1CYP1A2
SCHEMBL8086740 0.85 RORA (0.55) ALDH1A1MAPTTDP1L3MBTL1TP53
SCHEMBL29543602 0.85 RORA (0.55) ALDH1A1MAPTTDP1L3MBTL1TP53
SCHEMBL10022925 0.85 ALDH1A1 (0.85) ALDH1A1MAPTTDP1KDM4EHPGD
SCHEMBL29431235 0.85 ALDH1A1 (0.85) ALDH1A1MAPTTDP1KDM4EHPGD
SCHEMBL116890 0.85 ALDH1A1 (1.00) ALDH1A1PTGER4MAPTTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2223972-B1 Pigment composition, method of producing water-based pigment dispersion, water-based ink for inkjet recording FUJIFILM CORP (JP) 2013-10-16 EP disclosed
US-8529045-B2 Ink set and image forming method FUJIFILM CORPORATION (JP) 2013-09-10 US disclosed
US-8529045-B2 Ink set and image forming method FUJIFILM CORPORATION (JP) 2013-09-10 US disclosed
US-8511812-B2 Aqueous ink composition and image forming method FUJIFILM CORPORATION (JP) 2013-08-20 US disclosed
US-8511812-B2 Aqueous ink composition and image forming method FUJIFILM CORPORATION (JP) 2013-08-20 US disclosed
US-20110109708-A1 AQUEOUS INK COMPOSITION AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2011-05-12 US disclosed
US-20110109708-A1 AQUEOUS INK COMPOSITION AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2011-05-12 US disclosed
US-20110057987-A1 INK SET AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2011-03-10 US disclosed
US-20110057987-A1 INK SET AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2011-03-10 US disclosed
EP-2223972-A2 Pigment composition, method of producing water-based pigment dispersion, water-based ink for inkjet recording FUJIFILM Corporation (JP) 2010-09-01 EP disclosed
US-20100216936-A1 PIGMENT COMPOSITION, METHOD OF PRODUCING WATER-BASED PIGMENT DISPERSION, WATER-BASED INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2010-08-26 US disclosed
US-20100216936-A1 PIGMENT COMPOSITION, METHOD OF PRODUCING WATER-BASED PIGMENT DISPERSION, WATER-BASED INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2010-08-26 US disclosed
US-6054501-A CURABILITY; GLOSSINESS; CAN BE BLENDED WITH INKS, PAINTS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2000-04-25 US disclosed
EP-0844255-A1 PHOTOPOLYMERIZATION INITIATOR AND ACTINIC RADIATION-CURABLE COMPOSITION COMPRISING THE SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1998-05-27 EP disclosed