Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086966 | 0.91 | ALDH1A1 (0.39) | TRPV1ALDH1A1RXFP1SMN1; SMN2KMT2A | |
| SCHEMBL8078916 | 0.88 | TRPV1 (0.48) | TRPV1ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL8085722 | 0.86 | ALDH1A1 (0.42) | TRPV1ALDH1A1RXFP1SMN1; SMN2KMT2A | |
| SCHEMBL8090408 | 0.85 | KMT2A (0.41) | ALDH1A1RXFP1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8183409 | 0.83 | TRPV1 (0.39) | TRPV1ALDH1A1RXFP1SMN1; SMN2KMT2A | |
| SCHEMBL5973535 | 0.77 | POLB (0.41) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL8078887 | 0.77 | POLB (0.41) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL8091960 | 0.77 | ALOX5 (0.51) | ALDH1A1SMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL8565866 | 0.76 | CYP19A1 (0.33) | ALDH1A1SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL8086968 | 0.76 | CTSB (0.43) | ALDH1A1KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1137886-C | 2,3-dioxo-1,2,3,4-tetrahydro-quinoyxalinyl derivatives | ��˹��ŵ�� | 2004-02-11 | — | — | CN | disclosed |
| US-6080743-A | AS CHEMICAL INTERMEIDATES FOR PREPARING DRUGS | NOVARTIS AG (CH) | 2000-06-27 | — | — | US | disclosed |
| CN-1193968-A | 2,3-dioxo-1,2,3,4-tetrahydro-quinoyxalinyl derivatives | NOVARTIS AG (CH) | 1998-09-23 | — | — | CN | disclosed |
| EP-0853617-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | Novartis AG (CH) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997008155-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | disclosed |