Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095688 | 0.88 | HDAC1 (0.41) | LMNALRRK2NPC1RAB9ADUSP3 | |
| SCHEMBL8087171 | 0.76 | DUSP3 (0.58) | LMNANPC1RAB9ADUSP3KMT2A | |
| SCHEMBL8087450 | 0.73 | MAPK1 (0.59) | LMNANPC1RAB9ADUSP3ALDH1A1 | |
| SCHEMBL8096406 | 0.73 | DUSP3 (0.72) | LMNANPC1RAB9ADYRK1ADUSP3 | |
| SCHEMBL8094946 | 0.65 | DUSP3 (0.55) | LMNANPC1RAB9ADUSP3ALDH1A1 | |
| SCHEMBL14807437 | 0.64 | MAP3K5 (0.68) | LRRK2NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL8095230 | 0.64 | DUSP3 (0.67) | LMNANPC1RAB9ADYRK1ADUSP3 | |
| SCHEMBL21091465 | 0.64 | DYRK1A (0.61) | NPC1RAB9ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL23657486 | 0.63 | ALDH1A1 (0.69) | LMNANPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL6057617 | 0.63 | LCK (0.50) | NPC1RAB9AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604657-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2000-01-12 | — | — | EP | claimed |