Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1482271 | 0.90 | THRB (0.54) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL632865 | 0.90 | TSHR (0.55) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL6652309 | 0.89 | THRB (0.56) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL4849126 | 0.89 | THRB (0.56) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15081586 | 0.85 | THRB (0.56) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL9805448 | 0.85 | TSHR (0.58) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL6509806 | 0.84 | THRB (0.54) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL2367366 | 0.84 | THRB (0.54) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL15477542 | 0.83 | TSHR (0.61) | THRBTSHRALDH1A1POLBAPEX1 | |
| SCHEMBL1023058 | 0.83 | TSHR (0.61) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639576-B1 | Organopolysiloxanes having a silanol group and process of making them | SHINETSU CHEMICAL CO (JP) | 2000-10-11 | — | — | EP | disclosed |
| US-5508369-A | ROOM TEMPERATURE CURABLE LIQUID SILICONE RUBBER | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0639576-A1 | Organopolysiloxanes having a silanol group and process of making them | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-02-22 | — | — | EP | disclosed |